About

“In its current format, iGEM aims to improve societal aspects relevant to local communities, and thus encourages young researchers all around the world to identify and tackle challenges critical to their region with practical synthetic biological devices and technologies.”

In 2021, we announced a special issue of the Synthetic and Systems Biotechnology journal on The 2019 and 2020 iGEM Proceedings ↗. A special thank you 💚 to our collaborators KeAi Publishing ↗ for creating this opportunity for iGEMers to publish their iGEM projects in their journal, and Bluepha ↗ for sponsoring the Article Processing Charges (APCs) for iGEM teams.

KeAi
Bluepha

Through this collaboration, 12 iGEM Teams from the 2019 and 2020 iGEM Competition published their work and showcased how synthetic biology can advance the field through applications in bio-sensing and therapeutics to bioremediation and the development of novel and stable bio-materials. These projects ranged from creating drug delivery platforms for targeted recognition of cell membrane receptors in breast cancer patients, constructing toehold switches and microRNA based detection circuits for cervical cancer to protein-based fire retardants, degradation of perfluorinated compounds (PFC) by engineering of PFC-degrading enzymes and much more! Take a look at all the published papers available for open access below:

paper

Editorial for “Special Issue on the 2019 and 2020 iGEM proceedings”

Roger Rubio Sanchez
paper
New Application

Toehold switch based biosensors for sensing the highly trafficked rosewood Dalbergia maritima

Evry Paris-Saclay 2020
paper
Therapeutics

Bioengineering bacterial encapsulin nanocompartments as targeted drug delivery system

UCL 2019
paper
New Application

Aptamer-based cell-free detection system to detect target protein

XMU 2018
paper
Software

Classification of protein domains based on their three-dimensional shapes (CPD3DS)

UESTC 2020
paper
Manufacturing

Expression of heat-resistant β-glucosidase in Escherichia coli and its application in the production of gardenia blue

SZU 2020
paper
High School

Engineering a Cell-Penetrating Hyperstable Antibody scFv(Ras) - An Extraordinary Approach to Cancer Therapeutics

Korea HS 2020
paper
High School

Using recombinant adhesive proteins as durable and green flame-retardant coatings

Pui Ching Macau 2020
paper
Foundational Advance

finDr: A web server for in silico D-peptide ligand identification

Freiburg 2019
paper
Manufacturing

Study on RNAi-based herbicide for M. micrantha

SZU 2019
paper
High School

Expression, secretion and functional characterization of three laccases in E. coli

Pui Ching Macau 2020
paper
Environment

Engineering and characterization of dehalogenase enzymes from Delftia acidovorans in bioremediation of perfluorinated compounds

USAFA 2020
paper
Diagnostics

End-to-end computational approach to the design of RNA biosensors for detecting miRNA biomarkers of cervical cancer

SASTRA 2019

Through such efforts we want to continue our commitment to continued education of iGEMers after the competition by providing them an opportunity to publish their scientific research in a peer-reviewed journal filled entirely with iGEM Projects!